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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57449910d9cdf4ac73c91cd407cceca4f95a36c80de9caf1e42a2ec09ec6dc9c' 
  AND token = 'mtoBoAaMOTIN/wdrujccCDg6TRyP6u9KA4cZHxB4cDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}