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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a00f3a4dc2e9878ea733b322cb0ddf0e4b70c7dbb89e3d5d0c453fe72444405' 
  AND token = 'z2AXikmeLTS7ppImkTl9Ablx6OPLKQsXWUYvMstw6OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}