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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffcb2a245f7e7092b86c54a651fe7117dd8bd033e1c8fcf018c0654222a6502d' 
  AND token = 'IuNT99D4o0SFB0OAaPKV4V74mUkXcVoGtPvq5FEJOjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}