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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0812445e30df6e0d04d9b02042b67fc9f5ffd01a7dcddf3121776ab1038ca29' 
  AND token = '2yJQ1CLomD/WuZ4QcUmUbKpcfMpyCmpYTaVtEE9Gwc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}