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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067cb6cd3f20d0249c0c788d7faafbedfd4a2e88c33fd4e1e56d94cecec1778d' 
  AND token = 'Uw2hc4C5u9vqEBPKXyZ5rQaxfBMvghZbI/+lvx2g2uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}