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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d29bee245a01750b639253a241bd8e59b7414039625ae1fe541053c027be57' 
  AND token = 'KAJWDgb1dpcy6sFRaHu2Dm4Y02WC2sjzJ4UaUdBQtPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}