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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81d73c648cf3c382a0bae20e872d76c7e5b0e81f3ebc00bd810e6e93b3eb645' 
  AND token = 'RigA9XQMp7hpwvLkUkSJcCKP5JWwo+T2O9KcQ7ws9dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}