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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1cef5cd75c52618819dd47f9bac6b8465247d83f1046528d3d8d51e5036b9a' 
  AND token = 'me8X43tBWo6SaWUkrmp+ieZixdg1Oyj7ZgLmajVZxIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}