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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a886135a399fe58cd5c7670a657e969afcce61626536ae25635051086974f629' 
  AND token = 'UAk+5z0vS0ehYW1ps/0nGWkPkUbkpogNnFplCmrg7Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}