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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533fcfd2a71303a19378749d2cd96e37d3919e6a3d840ab7a13955751d8c63dd' 
  AND token = 'nhvy2oPVPbtA7qBEaUSPKTqI7hWWDD2oUtFlyuqNVqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}