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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3ef5a7b8013e11cb12bd605efc9cb622a812575203ef87825e60d5ca0081b8b' 
  AND token = 'Eo7B+0jWR3wRYm6tkckxJG7X3RkXDZpBFSKV2+oSAIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}