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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f646fc34f5537d75939ef99aaa901ef6ca510ff78211e8e8802c4cb4319a9c94' 
  AND token = '8032tQ40wXtGuctnn/upmchAQaq1v6Iws+mcydfn69M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}