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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22cec7ed6e7da27c81e4b2872bcd721a3578a67307d9e31d33fe2a229ef846e' 
  AND token = '6vZaP6qyyPIDqwA0Md0ywZY1awrkP0dJdTKzUVdcieA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}