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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0063a54b591516826f377c1956d50d8cfbe86020bb100be1c3831cf6dd2d249' 
  AND token = 'tqscXYzNswga58TxrG0QQUJ4YmywaOAFf7ucemUvpWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}