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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e644ecbc62cffdcb6ea6e4a9c137c02c237880666ba75f02694551c967bdf813' 
  AND token = 'Ff4X5hGiCoPFlUPrtTuq8ckJ1ZOfRS5V6AIkky8DO34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}