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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f175833f4826b5e0ef6feca656a30ff2baeea633bf11c28254d415369b148445' 
  AND token = '2hS5SkfaWd8c1QN7Bxjz+2EqeNF3FC5dUARxDnE0ft4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}