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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec9c2ac39dbd03580951e7f1e04b388c6a9e6a0faf18dec8147eafff918f586b' 
  AND token = 'kkUYe+hL7OjbvtfGlL7CNvRc6VPAsqtcD1zbnoLwwq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}