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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08143592eb7ab953104e6512026aebcba8a7a957c12da0a70074104452281888' 
  AND token = 'h4UYNfihhtT+uN+VrCTEup/E04+cIer+1UvQcPV9Z90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}