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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e461b34ab3c5641b49da19d66fac0ef2a6b7db1196a16f2e8086464b0942a997' 
  AND token = 'q3DeC4FAn9nGizRuqOOQD3NLc7oxD61Z/LAJ5MVu7dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}