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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '473d5fe0c6b9c41a2081c370c4ee6564e897c651f1b9df02225ffbc3cf088d9b' 
  AND token = 'FfdJl6DmxbSWHPbNrR4rReNRM34ANbrCfjD3fixQ0aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}