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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f598609543165a71e5d6db395b05e61fae9a103ac7f0fba36123f265b6c42ea' 
  AND token = 'dINxZ8k/JxVfLlvA0bjTbYey/T9+5yETlmK8GPR0bSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}