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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a3a5f825f0223c97bd5f01f7577a643517b9ef92e5a587f295d14ba9204241' 
  AND token = '1kV/lhrQEywLnuSD15AhiWIFT6lzy1YwV0jjxnmrbsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}