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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0782928921524a8cc1ff0a73b8544498d36c5983cf217a6c6447b710f32e08' 
  AND token = 'IA9bSQ3IusAgr7SYx/kK/C6MBtRzBNeXVfPy34xzbc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}