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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4e59a5091a54fbb7d9674e133189ca78e4e45764c9330452229d6d51c85c25' 
  AND token = '2E0DsTsrMjbvhhpj5zy09WBP9NurWmP2UYJyhXFQeeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}