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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f91f3e53a1147c4f9953ab8240b481f5533671825ec6d232b3df18ef8c86f4' 
  AND token = 'YTE889nCL180JN2Z8a+S7FEfa9ChVLmcC0dGY0UKqMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}