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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2856bf168c9b3deb58843c224c02015a38aee5763b9d09598b480aab5e23b56f' 
  AND token = 'BC8Cuoowv3NENSpIrZKgVtRhqE65hCPLsGy9Hxg8HQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}