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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48678528e0c11f90876ddbb8900d94e6863470282dce9cb79def5a31807f811a' 
  AND token = '2N/mnEUgALS90M7ls3CHHCWwxH0uksiU/tX5qt90zLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}