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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fc2ab49764d658dbc4257f665bc44dca4e132cee7b23248fa86d02d4575af0' 
  AND token = 'HoS8NK2EhAI4sFQZ7MKtvBLpBHmUTo83Vh90Va16l24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}