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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffbd8d880e62172401c9650a644baf223fc44a3310f7a9249dd552800cef68d8' 
  AND token = 'p6lBEvCZ0WNtkAg1YqDxEio6pqEVROvCXQT7/Qg61RY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}