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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd12d827e8d58a06702afab00b54eaa3fa12ea6429988ee78d465911c0a18c58e' 
  AND token = 'hae91O98ucBsOIyIKwXzLBsNfCDWNpW3dzXeT7stbA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}