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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a053387e5238453f74fb4efeee241bf84b574ff30b7abe54fadc006fe3630c' 
  AND token = 'laFZ21/gGNx4dxKP7JSVIjwUWyN3QnfO0pNVtAitFfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}