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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d8868d7180a83250d3f1e1118c4db7e15203f4243104228a97aa384a5d206e' 
  AND token = 'jntHb19T0lq/uuaGrzkK/kJ5D0aDBAH8jTZ6oItRZHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}