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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a22d7bddadba0582eba6dc486b3bda6de1604279a3dc19ea98b5803f99b659' 
  AND token = 'jFYPFosypKfX5q2tLA9RzZiXQkoErB2sAFlpG4gjnqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}