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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54bd43cf2f03df92758e8266b7136416abae1d7e8adef544246279ff23cd1830' 
  AND token = 'JaQ48ZpJ0lyiLmwa/UrI/5e99nDeYbFXry7ENgo36r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}