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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7d1e77bd005ed7ef5f34c72039267059643fd267cf130cbc9ec347ed3bff214' 
  AND token = 'lj/JVX82N+W4WRalnZPWWcIdE5trNXx1VnJXN54D5EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}