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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c86b4b51b433b6b9ef540e55c5038d0080c59cdd74b81ebac785607e8fc8e28' 
  AND token = 'OsIEzsDPf4MVGsWqn4156Y/7rQhhWMiZvR0lDw2x8WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}