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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6be500a8e6e0f3e2b1bd33857afdfe541e83fd822272efb49df16733922a6e9c' 
  AND token = '8E9TDac6qMZ020r/J2x3VcwLtZWCteqZPCopRfePGNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}