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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6577a9fc17ec9291b6da7a9369acc410f3d6d59f25366c6f35a62344c6c905' 
  AND token = '603GcJbD4U6N8p/70k36yYZstn+CowEO63JEHeyYUHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}