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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c6504145aff54921a15522384ce288b1c5c06b827d3ca222f18827b1cbbfbe0' 
  AND token = 'tiRNoClPDTwYiSr26Ly/g2u7059gI/bQfZvkfeIn/ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}