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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '961ceaa7e50627eaf7dc70643f9d02251372a018ee06887f0ab4032fff1580cd' 
  AND token = 'jMRQN2/qzgbuH0JobX/QdrTwh1CLXD3fS+13lxtHvvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}