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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b144eeaa6eda44472fbbd5393f6d8c8a5e623ca33b5d67eddbf92c21c908e2b8' 
  AND token = 'wummFsz2gYuEjxSieD3846VSPt0PAnA/E2/VxQwSxXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}