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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561863cce336765849e8794992e8d3a8adc6350e2a5adaea5377ba01237a386b' 
  AND token = 'CMR2mKxeDsTJrI8SPzr5Nawi24bjlyoeJHHZhhUSrag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}