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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bff50c68458be3d480fd4960ed36ecd9acb89dccd0e916e5789c1c82be56cd5' 
  AND token = 'ZOZuoYVTc51vH/b5KPOuMhdNNJVFiiW8wBIKQnTpX14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}