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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9002e7a118e5d721053c0c22f4e971e3bd884fd73adb0fa26c15b720834dcac5' 
  AND token = 'imBiS1ct6DC0ETmf/6CZGMw3snUbxHpI46DKIZIWNB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}