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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aefd3a337ecf1053d607818c44739d408c2e3447d3e8bb882a9b864ab18e95a9' 
  AND token = '2uzMmyNLwkZrca5sMCW0rKALOwv4kFwS0TODvDH4RjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}