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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b83b5d195e75bf3c6e69b61afa04afeba10e4c0517382a07164d318c85f889f' 
  AND token = 'p5py3rL20u0lhxajBEuQTrrWjsKBoPWiqcyeqc3SARM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}