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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a927493c7fdcec2af6edd1bef7ad7b3d283a8ad6a86fee0a93bcf274df5dda4b' 
  AND token = 'deR10rHZY65uclIRP2Q/qLumRGxxcqX0WcCabhF+nas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}