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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f0f65ed0fa6797e7ffdff5f9de2b4bf4e2fbe409fc38146945b83b91f3780b' 
  AND token = 'Mud5cdn1HS8C32RV15Lmw/rk6fFysaVpwF1Tz7yHaNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}