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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e541956700b0e5e83b0c4867b470fd95ef750d9bcc23a06668d2459f6d931bdc' 
  AND token = '/Ho/ftILB6Y7mypN4Ynpd88UTSE7OfuDg4lZTT4alZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}