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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45f396109d13903dfcd50edcff6f16bea526203ca64a32313598170d660e044' 
  AND token = 'Hwr8xzggrZWz8hX3M9QSxQutsy+fC5JdddHuFuACfjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}